Skip to main content

Table 4 Joint association between CAR and Physical Activity with all-cause and cancer mortality among US cancer survivors age 40 years or older, NHANES, 1999 to 2010

From: Combined influence of physical activity and C-reactive protein to albumin ratio on mortality among older cancer survivors in the United States: a prospective cohort study

Mortality Outcome

Physical Activity (MET-min/week)

Death/No

Hazard ratio (95% CI)

Non-adjusted Model

Model Ia

Model IIb

All-Cause

     

 CAR (low)

None(inactive)

108/186

0.73 (0.58 ~ 0.92)

0.60 (0.48 ~ 0.76)

0.60 (0.48 ~ 0.76)

< 600 (insufficiently active)

96/223

0.38 (0.30 ~ 0.49)

0.43 (0.34 ~ 0.55)

0.43 (0.33 ~ 0.55)

≥ 600 (sufficiently active)

1125/330

0.39 (0.31 ~ 0.48)

0.37 (0.3 ~ 0.47)

0.41 (0.32 ~ 0.51)

 CAR (medium)

None(inactive)

171/248

0.95 (0.78 ~ 1.16)

0.78 (0.64 ~ 0.95)

0.76 (0.62 ~ 0.93)

< 600 (insufficiently active)

121/223

0.50 (0.40 ~ 0.63)

0.49 (0.39 ~ 0.61)

0.51 (0.41 ~ 0.65)

≥ 600 (sufficiently active)

115/276

0.43 (0.35 ~ 0.54)

0.42 (0.34 ~ 0.54)

0.45 (0.35 ~ 0.56)

 CAR (high)

None(inactive)

229/325

1 [Reference]

1 [Reference]

1 [Reference]

< 600 (insufficiently active)

101/180

0.57 (0.45 ~ 0.72)

0.63 (0.50 ~ 0.80)

0.63 (0.50 ~ 0.80)

≥ 600 (sufficiently active)

108/241

0.49 (0.39 ~ 0.62)

0.55 (0.44 ~ 0.70)

0.59 (0.47 ~ 0.75)

Cancer

     

 CAR (low)

None(inactive)

24/186

0.55 (0.34 ~ 0.87)

0.49 (0.31 ~ 0.78)

0.52 (0.32 ~ 0.83)

< 600 (insufficiently active)

29/223

0.42 (0.27 ~ 0.65)

0.45 (0.29 ~ 0.71)

0.45 (0.28 ~ 0.71)

≥ 600 (sufficiently active)

30/330

0.32 (0.21 ~ 0.49)

0.31 (0.20 ~ 0.48)

0.32 (0.20 ~ 0.50)

 CAR (medium)

None(inactive)

45/248

0.83 (0.57 ~ 1.21)

0.76 (0.52 ~ 1.12)

0.71 (0.48 ~ 1.05)

< 600 (insufficiently active)

25/223

0.37 (0.24 ~ 0.59)

0.38 (0.24 ~ 0.6)

0.36 (0.23 ~ 0.58)

≥ 600 (sufficiently active)

39/276

0.50 (0.34 ~ 0.75)

0.49 (0.33 ~ 0.74)

0.50 (0.33 ~ 0.75)

 CAR (high)

None(inactive)

68/325

1 [Reference]

1 [Reference]

1 [Reference]

< 600 (insufficiently active)

36/180

0.72 (0.48 ~ 1.08)

0.77 (0.51 ~ 1.16)

0.79 (0.53 ~ 1.20)

≥ 600 (sufficiently active)

39/241

0.61 (0.41 ~ 0.91)

0.69 (0.46 ~ 1.03)

0.72 (0.48 ~ 1.08)

  1. Abbreviations: CAR C-reactive protein-to-albumin ratio; US the United States, NHANES National Health and Nutrition Examination Survey, HR Hazard ratio, CI Confidence interval, MET the metabolic equivalent
  2. aMultivariable model adjusts for age, sex, race (Non-Hispanic White, Non-Hispanic Black, Mexican American, Other Race—including multiracial and other Hispanic), Marital status (Married or living with a partner, Living alone), educational attainment (less than high school, high school or equivalent, and above high school), family poverty income ratio (< 1.30, 1.30–3.49, or ≥ 3.5)
  3. bAdditionally adjusted for BMI (calculated as weight in kilograms divided by height in meters squared), smoking status (never, former, current), alcohol use (never, former, current), Healthy Eating Index-2015, hypertension (yes/no), history of diabetes (yes/no), cardiovascular disease (yes/no)
Back to article page

European Review of Aging and Physical Activity

ISSN: 1861-6909

Contact us